The bacterium, whose name means 'strange berry that withstands radiation,' is the most radiation-resistant organism known. In the second step, multiple proteins mend double-strand breaks through It has been known to withstand radiation levels of up to 1,000 times that which would kill a normal human, living up to its latin name, "strange little berry that withstands radiation." 2006 Aug 1;62(Pt 8):757-60. The name Deinococcus radiodurans derives from the Ancient Greek δεινός (deinos) and κόκκος (kokkos) meaning "terrible grain/berry" and the Latin radius and durare, meaning "radiation surviving".The species was formerly called Micrococcus radiodurans.As a consequence of its hardiness, it … Deinococcus-Thermus Class: Deinococci Garrity and Holt, 2002 Order: Deinococcales Rainey et al., 1997 Family: Deinococcaceae Brooks and Murray, 1981 Genus: Deinococcus Brooks and Murray, 1981 emend. Fig. 5. Deinococcus radiodurans, or “Conan the Bacterium,” survives in the harshest conditions on earth. 5. Most organisms are … Scientific name i: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) ... Terminal (leaf) node. If just one of these remains unchanged, it can survive. These folds are linked by a connector peptide (yellow, … Effect of a recD mutation on DNA damage resistance and transformation in Deinococcus radiodurans. D. radiodurans viewed by light microscopy. Bioremediation with D. radiodurans can be much cheaper and save a great amount of time. Deinococcus radiodurans … because it chills in nuclear waste. Multiple components distributed … However, it is known that multiple copies of each gene are found on all the chromosomes and plasmids, which most likely contributes to its amazing repair capabilities associated with its radiation resistance. Journal of Bacteriology. in the ground and in excrement, but also in nuclear reactors. The real challenge here isn't trying to insert random proteins into other species, but is making the protein expressive and recombinant, essentially self-sustaining in the new species. Rainey et al., 1997 Species: Deinococcus radiodurans (ex Raj et al., 1960) Brooks and Murray, 1981 Science 286, 1571-1577 (November 19, 1999). The Guinness Book of World Records says that Deinococcus radiodurans is the world’s most extremophile bacterium. Acta Crystallographica, Section F Structural Biology Crystallization Communications. Nothing could be further from the truth. 4. It has so many other brother and sisters from the same genus. D. radiodurans has since been isolated from a variety of habitats, mostly soil and feces based. These numerous soil dwellings have led many to classify D. radiodurans as a soil bacteria. A Microbial Biorealm page on the genus Deinococcus radiodurans, Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae; Deinococcus, Deinococcus radiodurans was first discovered in 1956 in a can of ground meat that had been treated with large doses of radiation to remove all hazardous bacteria from the product. Deinococcus radiodurans — The Consumate Survivor. The complete sequence of the R1 strain has 3,284,156 base pairs made up of two circular chromosomes (2,648,638 and 412,348 base pairs), a major plasmid (177,466 base pairs), and a small plasmid (45,704 base pairs). Deinococcus (from the Greek: δεινός, deinos, "dreadful, strange" and κόκκος, kókkos, "granule") is one genus of three in the order Deinococcales of the bacterial phylum Deinococcus-Thermus highly resistant to environmental hazards. Common name i-Synonym i-Other names i ›Deinococcus radiodurans R1 ›Deinococcus radiodurans str. DEINOCOCCUS RADIODURANS (1999) As its name implies, the Gram-positive bacterium Deinococcus radiodurans is the most radiation-resistant organism identified to date, being 200 times more tolerant of ionizing radiation and 20 times more resistant to ultraviolet radiation than E. … 3. 2. Common name; العربية: ... Deinococcus radiodurans‎ (5 F) Media in category "Deinococcus" The following 2 files are in this category, out of 2 total. Finally, the deeply branching bacterium Deinococcus radiodurans belongs to a genus whose name is derived from a Greek word meaning terrible berry. Deinococcus radiodurans is bolded in black next to Thermus thermophilus showing they have a common ancestor. Cavalier-Smith calls … You always thought you were alone. Cox, M., Battista, John. Deinococcus radiodurans — The Consumate Survivor. Nicknamed “ Conan the Bacterium ,” D. radiodurans is considered a polyextremophile because of its ability to survive under the many different kinds of … Cloning and expression of superoxide dismutase gene from Deinococcus radiodurans in E. coli. 1. The bacterium, whose name means 'strange berry that withstands ra… So far this research has not been completely successful, however it has as the team put it "provided the foundations for further studies and applications of the recombinant Mn-SOD."[6]. First, D. radiodurans reconnects some chromosome fragments by a process called single-stranded annealing. Obiero J, Bonderoff SA, Goertzen MM, Sanders DA. This page was last edited on 7 July 2011, at 15:14. D. radiodurans is a gram-positive bacteria, which exhibits significant resistance to ionising radiation. White, O. et al. This … One such research team in China is debating this topic. Sichuan Da Xue Xue Bao Yi Xue Ban. It can survive cold, dehydration, vacuum, and acid, and is therefore known as a polyextremophile and has been listed as the world’s toughest bacterium in The Guinness Book of World Records.. D. radiodurans … Habitat. Other names i ›"Micrococcus radiodurans" Raj et al. It has even been found on the inside walls of nuclear reactors. Deinococcus radiodurans was the first species of the genus Deinococcus that was isolated, and was also the first Deinococcus species for which the genome sequence was thoroughly analysed (White et al.1999; Makarova et al.2001). Finally, the deeply branching bacterium Deinococcus radiodurans (Figure 2) belongs to a genus whose name is derived from a Greek word meaning terrible berry. The microbes can deal with extreme cold, lack of water, vacuums and high acidity. As its name suggests, this bacterium can deal with radiation. Being a mesophile, this species grows relatively well between 30-37°C. DeWeerdt, S. E. The World’s Toughest Bacterium. Deinococcus radiodurans was first discovered in 1956 in a can of ground meat that had been treated with large doses of radiation to remove all hazardous bacteria from the product. It is often cultured in the lab from the feces of animals, such as elephants. Deinococcus radiodurans. Truepera radiovictrixDSM 17093 9. Expression, purification, crystallization and preliminary X-ray crystallographic studies of Deinococcus radiodurans thioredoxin reductase. Since then, D. radiodurans has been discovered in a wide variety of habitats.The mechanisms of survival allow it to withstand long periods of desiccation. Deinococcus desertiVCD115 6. D. radiodurans has within it, for example, multiple copies of its genome. Radioactive Man: Deinococcus radiodurans. Deinococcus radioduransR1 2. It is a non-pathogenic bacteria meaning thereby that it does not causes disease. Expression, purification, crystallization and preliminary X-ray crystallographic studies of Deinococcus radiodurans thioredoxin reductase. Servinsky MD, Julin DA. Since it is thought that the radiation resistance of D. radiodurans relies heavily on the cell's specialized proteins and cell structure, much research has been done to elucidate the structures of these proteins. It is possible that we could learn a lot from this bacterium. Science 286, 1571-1577 (November 19, 1999). This organism is interesting because of its extreme resistance to DNA damage induced by ionizing radiation ().It exhibits detectable survival after irradiation of 15,000 Gy and grows continuously at 60 Gy/h ().The unusual radiation resistance of D. radiodurans … Thermus thermophilusHB8 4. Genome News Netowrk, July 5, 2002, Edited by Edwin Cook, student of Rachel Larsen and Kit Pogliano, From MicrobeWiki, the student-edited microbiology resource. 1. Servinsky MD, Julin DA. Among these extremophiles, Deinococcus radiodurans is an important organism because it can able to survive in high radiation, ionizing and non-ionizing exposure (Slade and Radman, 2011). Deinococcus radiodurans. DeWeerdt, S. E. The World’s Toughest Bacterium. Nicknamed “ Conan the Bacterium ,” D. radiodurans is considered a polyextremophile because of its ability to survive under the many different kinds of extreme … Deinococcus radiodurans is an extremophilic bacterium, one of the most radioresistant organisms known. However, many scientists have found it peacefully existing in the soil of various settings, including the rocky granite of Anartica's dry valleys. GenBank. (A) Schematic diagram of D. radiodurans SSB primary structure.Two OB folds are present in each D. radiodurans SSB monomer: one is N-terminal (blue, residues 1–108), and one is C-terminal (red, residues 129–233). Figure 2 - D. radiodurans genetic engineering.png 1,360 × 1,562; 224 KB Play media Reconstitution in 6 phases, of the changes in cell shape (in red) and nucleoid structure (roughly equivalent to the DNA, in green), during the cell cycle of the bacteria D. radiodurans.webm 1 min 0 s, 1,920 × 1,080; 3.84 MB Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1. Deinococcus radiodurans, or D. radiodurans, is a bacterium which is thought to be the most resilient in the world. 2006 Aug 1;62(Pt 8):757-60. 1960 ›ATCC 13939 ›CCUG 27074 ›CIP 104750 ›DSM 20539 More » ›Deinococcus radiidurans ›Deinococcus radiodurans (ex Raj et al. Introduction. 6. This reductase is an enzyme that is found to be a crucial player in the cells response to oxidative stress, including double-strand DNA breaks. This significant finding suggests that this RecD-like protein in D. radiodurans is an important part of the repair system it uses. D. radiodurans is already known to be able to break down solvents such as toluene, but work needs to be done to try and make the bacteria capable of breaking down other compounds and materials that are common at radioactive waste sites.[7]. The great relief is its non-disease producing property. D. radiodurans is a gram-positive bacteria, which exhibits significant resistance to ionising radiation. These bacteria have thick cell walls that give them gram-positive stains, but they include a second membrane and so are closer in structure to those of gram-negative bacteria. Meiothermus silvanusDSM 9946 8. Name and classification. [5], Perhaps the most interesting current research taking place concerns whether or not it is possible to genetically make other bacteria as radiation resistant as D. radiodurans. That is where Deinococcus radidurans comes into play. Thermus thermophilusHB27 3. ... At the tip of that stalk there is a bit called the holdfast, which lives up to its name … The Dienococcus is genus and radiodurans is a species name. Nucleic Acids Res 2000 Jan 1;28(1):15-18. Nucleic Acids Res 2000 Jan 1;28(1):15-18. Deinococcus radiodurans is a gram-positive, nonsporulating bacterium which usually grows in tetrad form. Deinococus bacteria are ubiquitous in nature and have been isolated from various … Genome News Netowrk, July 5, 2002, https://microbewiki.kenyon.edu/index.php?title=Deinococcus_radiodurans&oldid=64949. Nature Reviews Microbiology 3, 882-892 (November 2005). [4], Yet another interesting point about this species is that it is able to quickly and accurately repair double-strand breaks in its DNA without the normal RecBCD enzyme that is present in other bacteria. Biology Deinococcus radiodurans; Structural Biology of Deinoccocus radiodurans Background. The name, ‘Deinococcus radiodurans,’ has been derived from the Greek language which literally translates to ‘strange-berry.’ It is a Gram-positive, nonpathogenic bacterium with an average cell diameter of 1 μm. D. radiodurans also has an extremely efficient DNA repair mechanism. Many researchers believe this relates to the reason why it can withstand so much radiation. Deinococcus radiodurans … because it chills in nuclear waste. Because D. radiodurans does not actually degrade the toxins, it will be used in conjuction with microbes that can degrade. It had been shown that deletion of the recD gene has led to substantial increase in sensitivity to radiation. Since they started researching its genome, scientists have discovered various mechanisms in the bacterium which protect it against mutation. Common name i-Synonym i-Other names i ›Deinococcus radiodurans R1 ›Deinococcus radiodurans str. Meng L, Xu X, Wang DL, Zhan L, Pei XF. The class Thermotogae is represented mostly by hyperthermophilic, as well as some mesophilic (preferring moderate temperatures), anaerobic gram-negative bacteria whose cells are wrapped in a peculiar sheath-like outer membrane called a toga. It has even been found on the … Cloning and expression of superoxide dismutase gene from Deinococcus radiodurans in E. coli. There is no current findings that suggest that D. radiodurans significantly interacts with other organisms in nature. Deinococcus marmoris Phylogeny.jpg 666 × 832; 86 KB. Deinococcus geothermalisDSM 11300 5. It is able to cope without air, water and food, and can withstand very high doses of radiation which would kill a human. If there's a superhero of the bacterial world, it's Deinococcus radiodurans. DEINOCOCCUS RADIODURANS (1999) As its name implies, the Gram-positive bacterium Deinococcus radiodurans is the most radiation-resistant organism identified to date, being 200 times more tolerant of ionizing radiation and 20 times more resistant to ultraviolet radiation than E. coli (White et al., 1999). However, current research has shown that D. radiodurans contains a gene sequence that encodes for a protein that is very similar to the RecD enzyme found in E.coli. Because D. radiodurans does not actually degrade the toxins, it will be used in conjuction with microbes that can degrade. Radioactive Man: Deinococcus radiodurans Myxococcus spores can resist heat and dryness, but they look pretty wimpy compared to Deinococcus radiodurans. The name, ‘Deinococcus radiodurans,’ has been derived from the Greek language which literally translates to ‘strange-berry.’ It is a Gram-positive, nonpathogenic bacterium with an … Due to its interesting cell structure and radiation resistant properties, D. radiodurans has been the focus of many current research groups. Structure of D. radiodurans SSB. Nicknamed “ Conan the Bacterium ,” D. radiodurans is considered a polyextremophile because of its ability to survive under the many different kinds of … Bioremediation with D. radiodurans can be much cheaper and save a great amount of time. May 11, 2007. Biology Deinococcus radiodurans; Structural Biology of Deinoccocus radiodurans Background. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Rapp BA, Wheeler DL (2000). 1. "By nature, it is selected to survive radiation damage very well," D. radiodurans can withstand without loss of viability a dosage that is 3,000 … Scientists have been fascinated by these tough bacteria for years. Latin name: Deinococcus radiodurans: Lives in the ground and in excrement, but also in nuclear reactors: Size: 1-2 µm: The Guinness Book of World Records says that Deinococcus radiodurans is the world’s most extremophile bacterium. It is capable of withstanding acute irradiation doses of 1 500 kilorads, a level hundreds of times higher than … Figure 2 - D. radiodurans genetic engineering.png 1,360 × 1,562; 224 KB Play media Reconstitution in 6 phases, of the changes in cell shape (in red) and nucleoid structure (roughly equivalent to the DNA, in green), during the cell cycle of the bacteria D. radiodurans.webm 1 min 0 s, 1,920 × 1,080; 3.84 MB That is where Deinococcus radidurans comes into play. Summary All 21 of the Nudix hydrolase genes from the radiation-resistant organism Deinococcus … And how is it that it can also withstand extreme radiation despite the fact that radiation does not occur in the natural world? So far, the toughest of all seems to be the bacterium Deinococcus radiodurans—able to survive doses of radiation a thousand times … Given the presumed sharing of debris generated from meteorite impacts amongst the early planets, origins of D. radiodurans might even be accidentally common between Mars and Earth. These bacteria have thick cell walls that give them Gram-positive stains, but they include … It is found everywhere; in sewage, furniture, fomites etc. Oceanithermus profundusDSM 14977 The two Meiothermusspecies were … 1960) Brooks and Murray 1981 ›HAMBI 1924 ›IFO 15346 ›JCM 16871 ›LMG 4051 ›LMG:4051 ›Micrococcus radiodurans ›NBRC 15346 … Since then this species has been intensely studied for its radiation resistant properties. This ability does not rely on some "magic" gene that protects it from radiation, rather, it seems that D. radiodurans is able to more efficiently repair double strand breaks in its DNA that result from radiation damage thanks to these extra copies and a few other special proteins. Deinococcus radiodurans is listed in the Guinness Book of World Records as \"the world's toughest bacterium.\" And for good reason: The microbe can survive drought conditions, lack of nutrients, and, most important, a thousand times more radiation than a person can. D. RADIODURANS. Acta Crystallographica, Section F Structural Biology Crystallization Communications. 2005 Mar;36(2):200-3. 7. Nature Reviews Microbiology 3, 882-892 (November 2005). The Nudix hydrolases of Deinococcus radiodurans WenLian Xu, JianYing Shen, Christopher A. Dunn, Seema Desai and Maurice J. Bessman* Department of Biology and the McCollum-Pratt Institute, The Johns Hopkins University, Baltimore, MD 21218, USA. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Rapp BA, Wheeler DL (2000). 2005 Mar;36(2):200-3. The bacteria Radiodurans shrugs off radiation better than any cockroach around. The bacteria labeled in yellow are the archeabacteria indicating that D. radiodurans is a close living relative of more primitive bacteria. Journal of Bacteriology. Since then this species has been intensely studied for its radiation resistant properties. 5. White, O. et al. Deinococcus radiodurans was first isolated when it spoiled a can of meat that had been sterilized using gamma radiation. Sichuan Da Xue Xue Bao Yi Xue Ban. [2], The genome of D. radiodurans consists of four major parts. Human cells only have one copy of the genome and do not have D. radiodurans’ quick and efficient DNA repair mechanism.

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